Self-limited colitis during the course of rubella and cytomegalovirus infection in an immunocompetent adult

Intern Med. 2004 May;43(5):404-9. doi: 10.2169/internalmedicine.43.404.

Abstract

We report a case of self-limited colitis in cytomegalovirus (CMV) infection in an immunocompetent adult. A 22-year-old man developed a high fever and diarrhea. Laboratory data revealed an increased number of lymphocytes and liver damage. Enzyme immunoassays for anti-virus antibodies revealed that the patient was recently infected with CMV and rubella. Colonoscopy revealed severe erosive and edematous mucosa that resembled ulcerative colitis (UC). The symptoms, laboratory data and colonoscopic findings improved without any medical treatment. This case indicates that UC-like self-limited colitis can occur in an immunocompetent individual during the course of CMV infection.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antiviral Agents / therapeutic use
  • Biopsy, Needle
  • Colitis, Ulcerative / complications
  • Colitis, Ulcerative / diagnosis*
  • Colitis, Ulcerative / immunology
  • Cytomegalovirus Infections / complications
  • Cytomegalovirus Infections / diagnosis*
  • Cytomegalovirus Infections / drug therapy
  • Cytomegalovirus Infections / immunology
  • Follow-Up Studies
  • Humans
  • Immunocompetence / immunology*
  • Immunohistochemistry
  • Male
  • Remission, Spontaneous
  • Risk Assessment
  • Rubella / complications
  • Rubella / diagnosis*
  • Rubella / immunology
  • Severity of Illness Index
  • Sigmoidoscopy / methods
  • Tomography, X-Ray Computed

Substances

  • Antiviral Agents