Somatostatin analog (octreotide) in management of neonatal postoperative chylothorax: is it safe?

Pediatr Crit Care Med. 2004 Jul;5(4):356-7. doi: 10.1097/01.pcc.0000123552.36127.22.

Abstract

Objective: Somatostatin and its analogs have recently been introduced in the treatment of chylous effusions in infants and children following surgery. The safety profile of this treatment in critically ill patients has not been fully evaluated.

Design: Retrospective case review.

Setting: Tertiary pediatric cardiac center.

Patients: A male infant born by cesarean section with a birth weight of 2.6 kg.

Interventions: None.

Conclusions: We report the association of postoperative chylothorax treated with somatostatin analog (octreotide) and necrotizing enterocolitis in an infant following aortic coarctation repair.

Publication types

  • Case Reports

MeSH terms

  • Aortic Coarctation / surgery
  • Cardiac Surgical Procedures / adverse effects*
  • Chylothorax / drug therapy*
  • Chylothorax / etiology
  • Gastrointestinal Agents / therapeutic use*
  • Humans
  • Infant, Newborn
  • Male
  • Octreotide / therapeutic use*
  • Postoperative Complications / drug therapy*

Substances

  • Gastrointestinal Agents
  • Octreotide