A seroepidemiologic study of hepatitis A in Spanish children. Relationship of prevalence to age and socio-environmental factors

Infection. 1992 Jul-Aug;20(4):194-6. doi: 10.1007/BF02033057.


Three child population groups from the Madrid area were studied for anti-HAV antibodies. Analysis was carried out with respect to age and socio-environmental factors. The population understudy was composed of 156 children, with ages ranging from 1 to 14 years; they were stratified in three socio-environmental groups (white-family unit, gypsy-family unit and orphanage), and also divided into subgroups according to age. As a whole, an age-related increase in prevalence was found. The overall seroprevalence by socio-environmental groups was: gypsy-family unit 63%, orphanage 46%, and white-family unit 23%. Significant differences between groups appeared from seven years on, being more marked among the eldest subgroups. Among the factors evaluated, hygienic-sanitary conditions and overcrowding influenced the high prevalence rate found in the gypsy-family unit subjects, whereas overcrowding appeared to be responsible for the higher prevalence in orphanage residents, as compared to white-family unit children.

MeSH terms

  • Adolescent
  • Age Factors
  • Child
  • Child, Institutionalized / statistics & numerical data
  • Child, Preschool
  • Family
  • Female
  • Hepatitis A / blood
  • Hepatitis A / epidemiology*
  • Hepatitis A / etiology
  • Hepatitis A Antibodies
  • Hepatitis Antibodies / blood
  • Hospitals, Public
  • Housing / standards
  • Humans
  • Hygiene / standards
  • Infant
  • Male
  • Prevalence
  • Roma / statistics & numerical data
  • Seroepidemiologic Studies
  • Socioeconomic Factors
  • Spain / epidemiology
  • White People / statistics & numerical data


  • Hepatitis A Antibodies
  • Hepatitis Antibodies