Abstract
[reaction: see text] An efficient route to benzo[a]carbazoles via a metalation-cross-coupling sequence has been demonstrated and its application to the synthesis of the antitumor and antiviral alkaloid 6-cyano-5-methoxy-12-methylindolo[2,3-a]carbazole has been achieved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents / chemical synthesis*
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / pharmacology
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Antiviral Agents / chemical synthesis*
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Antiviral Agents / chemistry
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Antiviral Agents / pharmacology
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Carbazoles / chemical synthesis*
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Carbazoles / chemistry
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Carbazoles / pharmacology
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Catalysis
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Indicators and Reagents
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Indole Alkaloids / chemical synthesis*
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Indole Alkaloids / chemistry
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Indole Alkaloids / pharmacology
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Indoles / chemical synthesis*
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Indoles / chemistry
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Indoles / pharmacology
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Molecular Structure
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Nostoc / chemistry*
Substances
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Antineoplastic Agents
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Antiviral Agents
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Carbazoles
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Indicators and Reagents
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Indole Alkaloids
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Indoles
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6-cyano-5-methoxy-12-methylindolo(2,3-a)carbazole