Nitric oxide: a new player in plant signalling and defence responses

Curr Opin Plant Biol. 2004 Aug;7(4):449-55. doi: 10.1016/j.pbi.2004.04.002.


There is increasing evidence that nitric oxide (NO), which was first identified as a unique diffusible molecular messenger in animals, plays important roles in diverse (patho)physiological processes in plants. NO functions include the modulation of hormonal, wounding and defence responses, as well as the regulation of cell death. Enzymes that catalyse NO synthesis and signalling cascades that mediate NO effects have recently been discovered, providing a better understanding of the mechanisms by which NO influences plant responses to various stimuli. Additionally, growing evidence suggests that NO signalling interacts with the salicylic acid and jasmonic acid signalling pathways.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Cell Death / drug effects
  • Models, Biological
  • Nitric Oxide / metabolism*
  • Plants / metabolism*
  • Signal Transduction*


  • Nitric Oxide