Objective: To report on the treatment with recombinant FSH of an azoospermic normogonadotropic patient with a Y-chromosome microdeletion.
Design: Case report.
Setting: An assisted reproduction center.
Patient(s): A 32-year-old patient with azoospermia.
Intervention(s): Histological testicular biopsy, Y-chromosome screening, FSH treatment, and intracytoplasmic sperm injection.
Main outcome measure(s): Fertilization, embryo development, pregnancy, and delivery.
Result(s): After 6 months of treatment with gonadotropins, a small number of spermatozoa were found in the patient's ejaculate and used for IVF, resulting in a successful twin pregnancy and the delivery of two healthy girls.
Conclusion(s): In this study, treatment with gonadotropins promoted the spermatogenesis process and led to the production of spermatozoa in a normogonadotropic azoospermic patient.