Phenol block for cervical dystonia: effects and side effects

Arch Phys Med Rehabil. 2004 Jul;85(7):1117-20. doi: 10.1016/j.apmr.2003.10.012.

Abstract

Objective: To report on the effectiveness and side effects of 2% phenol block in patients with cervical dystonia (CD).

Design: Case series.

Setting: A rehabilitation department at a university medical center in Japan.

Participants: Sixteen patients (11 men, 5 women; mean age +/- standard deviation, 43.4+/-11.2y) with CD. The cause of the CD was unknown, and all cases were refractory to the oral medication and rehabilitation therapy.

Intervention: Two percent phenol blocks guided by electromyography.

Main outcome measures: A blind analysis by neurologists of the Tsui score before and after 2 weeks of treatment with phenol block. Side effects were evaluated by another neurologist and patient report.

Results: There was significant (P=.0002) improvement in neck movement and position, based on a reduced Tsui score, after the phenol block. However, 4 patients had a complication of sensory disturbance of the transverse cutaneous nerve of the neck area. The sensory disturbances decreased gradually and disappeared within 3 months, whereas the effects of the phenol block continued.

Conclusions: Phenol block can reduce the impact of CD that is refractory to therapy.

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neck Muscles / drug effects
  • Nerve Block*
  • Neuromuscular Agents / administration & dosage*
  • Neuromuscular Blockade / methods*
  • Phenol / administration & dosage*
  • Torticollis / rehabilitation*

Substances

  • Neuromuscular Agents
  • Phenol