Long-term outcome of cerebral infarction in young adults

Acta Neurol Scand. 2004 Aug;110(2):107-12. doi: 10.1111/j.1600-0404.2004.00273.x.


Objectives: We analysed the long-term outcome of 232 young adults aged 15-49 years with first-ever cerebral infarction in 1988-1997 in western Norway.

Material and methods: Mortality, recurrence, epilepsy, functional state as evaluated by modified Rankin scale (mRS), and employment were analysed at follow-up (mean time 5.7 years).

Results: Twenty-three (9.9%) patients had died. Recurrence occurred in 9.9%, and post-stroke seizures developed in 10.5%. Recurrence was associated with diabetes mellitus (P = 0.005). Favourable functional outcome (mRS = 2) was found in 77.9%. The functional outcome was better in posterior than anterior circulation infarctions (P = 0.011). Unfavourable functional outcome (mRS > 2) was associated with diabetes mellitus (P = 0.001) and severity of neurological deficits on admission for the index stroke (P < 0.001). Only 58.3% were employed at follow-up.

Conclusion: This population-based study shows that, although the majority had favourable functional outcome, cerebral infarction had major long-term impact on young adults as evaluated by mortality, recurrence and employment status.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Cerebral Infarction / complications*
  • Cerebral Infarction / diagnosis
  • Cerebral Infarction / mortality*
  • Employment
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Marital Status
  • Middle Aged
  • Myocardial Infarction / complications
  • Norway / epidemiology
  • Prognosis
  • Recovery of Function
  • Recurrence
  • Seizures / complications
  • Time Factors