The molecular basis of insecticide resistance in mosquitoes

Insect Biochem Mol Biol. 2004 Jul;34(7):653-65. doi: 10.1016/j.ibmb.2004.03.018.


Insecticide resistance is an inherited characteristic involving changes in one or more insect gene. The molecular basis of these changes are only now being fully determined, aided by the availability of the Drosophila melanogaster and Anopheles gambiae genome sequences. This paper reviews what is currently known about insecticide resistance conferred by metabolic or target site changes in mosquitoes.

Publication types

  • Review

MeSH terms

  • Animals
  • Anopheles / genetics*
  • Culicidae / genetics*
  • Drosophila melanogaster / genetics
  • Houseflies / genetics
  • Sodium Channels / genetics


  • Sodium Channels