Prevalence of depressive and anxiety disorders in an assisted reproductive technique clinic

Hum Reprod. 2004 Oct;19(10):2313-8. doi: 10.1093/humrep/deh414. Epub 2004 Jul 8.


Background: Little is known about the prevalence of specific depressive and anxiety disorders in women before a new course of assisted reproductive technology treatment. Few studies have adopted the proper psychiatric diagnostic procedures.

Methods: All consecutive women visiting the assisted reproduction clinic of a university-affiliated medical centre, with the intention of starting a new assisted reproduction treatment course, were recruited. A psychiatrist made a diagnosis of psychiatric disorders using a structured interview, the Mini-International Neuropsychiatric Interview (MINI).

Results: Of a total of 112 participants, 40.2% had a psychiatric disorder. The most common diagnosis was generalized anxiety disorder (23.2%), followed by major depressive disorder (17.0%), and dysthymic disorder (9.8%). Participants with a psychiatric morbidity did not differ from those without in terms of age, education, income, or years of infertility. Women with a history of previous assisted reproduction treatment did not differ from those without in depression or anxiety.

Conclusions: Depressive and anxiety disorders were highly prevalent among women who visited an assisted reproduction clinic for a new course of the treatment. Demographic features and a history of previous assisted reproduction treatment were not risk factors for these psychiatric morbidities in the assisted reproduction clinic.

MeSH terms

  • Academic Medical Centers*
  • Adult
  • Ambulatory Care Facilities / statistics & numerical data*
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / epidemiology*
  • Depressive Disorder / diagnosis
  • Depressive Disorder / epidemiology*
  • Depressive Disorder, Major / diagnosis
  • Depressive Disorder, Major / epidemiology
  • Dysthymic Disorder / diagnosis
  • Dysthymic Disorder / epidemiology
  • Female
  • Humans
  • Interview, Psychological
  • Prevalence
  • Psychiatry / methods
  • Reproductive Techniques, Assisted*
  • Taiwan / epidemiology