Paroxysmal autonomic alterations mimicking epilepsy: a case report

Epileptic Disord. 2004 Jun;6(2):125-8.


A 22-year-old male patient presented with paroxysmal hyperhidrosis, mydriasis, hypertension, and tachycardia. Cranial and cervical MRI revealed focal atrophy in the high order zone of the central autonomic network and syringomyelia. His physical and neurological examinations were unremarkable. Physiological testing included EEG, SPECT, serum/urine tests and autonomic testing. A poor response was achieved with the medical and interventional procedures employed. As the central autonomic network is an integral component of the internal regulation system of the brain, any lesion, no matter where in the network, may lead to paroxysmal autonomic alterations mimicking epilepsy (Published with videosequences).

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anticonvulsants / therapeutic use
  • Atrophy / pathology
  • Autonomic Nervous System Diseases / complications
  • Autonomic Nervous System Diseases / diagnosis*
  • Autonomic Nervous System Diseases / drug therapy
  • Diagnosis, Differential
  • Electroencephalography
  • Epilepsy / diagnosis*
  • Frontal Lobe / pathology
  • Humans
  • Hyperhidrosis / complications
  • Hypertension / complications
  • Magnetic Resonance Imaging
  • Male
  • Mydriasis / complications
  • Tachycardia / complications
  • Temporal Lobe / pathology


  • Anticonvulsants