The IUBMB-endorsed transporter classification system

Mol Biotechnol. 2004 Jul;27(3):253-62. doi: 10.1385/mb:27:3:253.


We here describe the transporter classification (TC) system that provides a rational means of classifying all transmembrane transport systems found in living organisms. The availability of this system provides a framework for the use of bioinformatic technologies to answer fundamental questions about the functions, mechanisms, and evolutionary pathways taken for the appearance of these systems. Such advances are discussed.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Sequence
  • Biochemistry / methods
  • Biochemistry / standards*
  • Databases, Protein / standards*
  • Documentation / methods*
  • Evolution, Molecular*
  • Guidelines as Topic*
  • Internationality
  • Membrane Transport Proteins / chemistry*
  • Membrane Transport Proteins / classification*
  • Membrane Transport Proteins / standards
  • Molecular Biology / methods
  • Molecular Biology / standards*
  • Molecular Sequence Data
  • Terminology as Topic
  • Vocabulary, Controlled


  • Membrane Transport Proteins