Vaccination and allergic disease: a birth cohort study

Am J Public Health. 2004 Jun;94(6):985-9. doi: 10.2105/ajph.94.6.985.


Objectives: We examined the effect of vaccination for diphtheria; polio; pertussis and tetanus; or measles, mumps, and rubella on the incidence of physician-diagnosed asthma and eczema.

Methods: We used a previously established birth cohort in the West Midlands General Practice research database.

Results: We found an association between vaccination and the development of allergic disease; however, this association was present only among children with the fewest physician visits and can be explained by this factor.

Conclusions: Our data suggest that currently recommended routine vaccinations are not a risk factor for asthma or eczema.

MeSH terms

  • Asthma / diagnosis*
  • Asthma / epidemiology
  • Asthma / etiology
  • Child
  • Child, Preschool
  • Cohort Studies
  • Eczema / diagnosis*
  • Eczema / epidemiology
  • Eczema / etiology
  • England
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Physicians, Family
  • Vaccination / adverse effects*