Synchronous squamous cell carcinoma of the stomach, the lung and the skin

Onkologie. 2004 Jun;27(3):291-3. doi: 10.1159/000077981.


Background: The incidence of multiple primary cancers is reported to be 0.3-4.3%.

Case report: A 70-year-old man was admitted to the hospital because of fatigue, weight loss, epigastric pain with melena. A biopsy taken from a tumoral lesion in the gastric corpus revealed squamous cell carcinoma. A nodular lesion was also detected on the nasal columella and biopsy from this lesion also showed squamous cell carcinoma. Computed tomography performed as a part of metastatic work-up revealed a lesion in the left pulmonary lower lobe. Bronchoscopic biopsy from this lesion also demonstrated squamous cell carcinoma.

Results: We report a case with synchronous squamous cell carcinoma of the lung, skin and stomach and discuss the multiple synchronous occurrence of carcinoma with the same histopathology in different sites with a review of the literature.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Squamous Cell / diagnosis*
  • Carcinoma, Squamous Cell / secondary
  • Humans
  • Lung Neoplasms / diagnosis*
  • Male
  • Neoplasms, Unknown Primary / diagnosis*
  • Skin Neoplasms / diagnosis*
  • Stomach Neoplasms / diagnosis*