Germ-plasm formation and germ-cell determination in Drosophila

Curr Opin Genet Dev. 1992 Aug;2(4):543-9. doi: 10.1016/s0959-437x(05)80169-8.


Germ cells in Drosophila form in a specialized cytoplasm that is critical for germ-cell development. Several genes involved in this process have been identified. By studying the temporal and functional sequence of interactions between their products, these genes can be ordered into a pathway for germ-plasm formation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Drosophila / genetics*
  • Drosophila / growth & development
  • Germ Cells / physiology*