Specificity of cell adhesion in development: the cadherin superfamily

Curr Opin Genet Dev. 1992 Aug;2(4):621-4. doi: 10.1016/s0959-437x(05)80182-0.


Cadherins are major cell-surface receptors involved in specific cell adhesion during development. Recent results reveal the existence of a growing array of related molecules involved in various forms of cell-cell adhesion, including that mediated by desmosomes. Comparisons with other families of adhesion receptors suggest testable models for functions of the emerging cadherin superfamily in development and disease.

Publication types

  • Review

MeSH terms

  • Animals
  • Cadherins / physiology*
  • Cell Adhesion / physiology*
  • Humans
  • Signal Transduction / physiology


  • Cadherins