Auditory neural pathway evaluation on sensorineural hearing loss using diffusion tensor imaging

Neuroreport. 2004 Aug 6;15(11):1699-703. doi: 10.1097/01.wnr.0000134584.10207.1a.


Diffusion tensor imaging is a new in vivo tool not only for the assessment of white matter structural integrity but also for diagnosis and assessment of disease conditions which disturb tissue structural coherence. In this study, we investigated the integrity of auditory pathway in patients of sensorineural hearing loss by means of fractional anisotropy of water diffusion to see any subtle changes of auditory pathways resulting from sensorineural hearing loss. In addition, this study suggests that the diffusion anisotropy measured by diffusion tensor imaging is highly sensitive to otherwise subtle disease processes not normally seen with conventional magnetic resonance imaging or computed tomography contrast.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Auditory Diseases, Central / metabolism
  • Auditory Pathways / metabolism
  • Child
  • Diffusion Magnetic Resonance Imaging / methods*
  • Female
  • Hearing Loss, Sensorineural / metabolism*
  • Humans
  • Male
  • Middle Aged