[pH-Testing - experience in clinical practice in a pulmonary division]

Pneumologie. 2004 Jul;58(7):479-82. doi: 10.1055/s-2004-818535.
[Article in German]

Abstract

The association between lung disease and gastroesophageal reflux has been discussed for a long time. Aim of this retrospective study was to clarify evidence and acceptance of pH-testing in a pulmonary division.

Method: pH-testing data at the Krankenhaus Grosshansdorf from January 2000 till March 2004 was evaluated and clinical and pulmonary functional data assessed.

Results: A total of 186 patients (113 female, 73 male) received a pH-monitoring. The most important indication was chronic cough (94.6 %). Of 165 evaluable subjects, 63 patients had asthma, 54 patients chronic cough, 18 COPD and 30 patients various diseases (fibrosis, pneumonia, tuberculosis, bronchiectasis a. s. o.). 51 % of patients showed a pathological gastroesophageal reflux (median DeMeester score 22.3). Neither BMI nor patient subgroups correlated significantly with DeMeester score. In 62 % of asthmatics, 57 % of patients with chronic cough and 33 % of COPD patients a pathological reflux was found. In the subgroup with various diseases there was pathological reflux detected in 30 %.

Conclusions: pH-testing is a reliable and safe method to determine gastroesophageal reflux in pulmonary diseases. Pathological reflux is frequently found even without typical symptoms. It remains unclear whether there is a causal relationship.

Publication types

  • English Abstract

MeSH terms

  • Asthma / physiopathology*
  • Cough / physiopathology*
  • Female
  • Gastroesophageal Reflux / physiopathology
  • Humans
  • Hydrogen-Ion Concentration*
  • Lung Diseases / physiopathology*
  • Male
  • Monitoring, Physiologic
  • Respiratory Function Tests*
  • Retrospective Studies