Abstract
A polysaccharide from the water extract of cultured Cordyceps militaris was isolated through ethanol precipitation, deproteination and gel-filtration chromatography. Their molecular weight was determined using gel-filtration chromatography. The structure of polysaccharide CPS-1 was elucidated by sugar analysis, Smith degradation, IR and 13C-NMR spectroscopy. CPS-1 was shown to possess a significant antiinflammatory activity and suppressed the humoral immunity in mice but had no significant effects on the cellular immunity and the non-specific immunity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetic Acid
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Animals
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Anti-Inflammatory Agents / administration & dosage
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Anti-Inflammatory Agents / pharmacology*
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Anti-Inflammatory Agents / therapeutic use
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Capillary Permeability / drug effects*
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Cordyceps*
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Croton Oil
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Dose-Response Relationship, Drug
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Edema / chemically induced
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Edema / prevention & control*
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Erythrocytes / drug effects
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Female
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Hemolysis
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Hypersensitivity, Delayed / prevention & control
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Male
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Mice
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Mice, Inbred ICR
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Phagocytosis / drug effects*
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Phytotherapy*
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
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Polysaccharides / administration & dosage
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Polysaccharides / pharmacology*
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Polysaccharides / therapeutic use
Substances
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Anti-Inflammatory Agents
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Plant Extracts
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Polysaccharides
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Croton Oil
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Acetic Acid