Solid phase enzyme immunoassays for the quantification of serum amyloid P (SAP) and complement component 3 (C3) proteins in acute-phase mouse sera

Horm Metab Res. 1992 Aug;24(8):371-4. doi: 10.1055/s-2007-1003338.


Simple, reliable and sensitive enzyme immunoassays have been developed for the quantification of the mouse acute-phase SAP and C3 proteins. The ELISA systems were validated using sera from mice injected with S. dysenteriae endotoxin, and detected 500 pg protein/ml. The assays use 96-well microtitre plates permitting rapid processing of a large number of samples.

MeSH terms

  • Acute-Phase Reaction / blood*
  • Animals
  • Bacterial Toxins / toxicity
  • Complement C3 / analysis*
  • Enzyme-Linked Immunosorbent Assay
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Serum Amyloid P-Component / analysis*
  • Shiga Toxins
  • Shigella dysenteriae


  • Bacterial Toxins
  • Complement C3
  • Serum Amyloid P-Component
  • Shiga Toxins