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, 93 (4), 399-403

Further Evidence for Paternal Inheritance of Mitochondrial DNA in the Sheep (Ovis Aries)


Further Evidence for Paternal Inheritance of Mitochondrial DNA in the Sheep (Ovis Aries)

X Zhao et al. Heredity (Edinb).


The mitochondrial DNA of 172 sheep from 48 families were typed by using PCR-RFLP, direct amplification of the repeated sequence domain and sequencing analysis. The mitochondrial DNA from three lambs in two half-sib families were found to show paternal inheritance. Our findings provide direct evidence of paternal inheritance of mitochondria DNA in sheep. A total of 12 highly polymorphic microsatellite markers, which mapped on different chromosomes, were employed to type the sheep population to confirm family relationships. Possible mechanisms of paternal inheritance are discussed.

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