1,3-Propanediol production by Klebsiella pneumoniae under different aeration strategies

Biotechnol Lett. 2004 Jun;26(11):911-5. doi: 10.1023/b:bile.0000025902.44458.f4.

Abstract

1,3-Propanediol production by Klebsiella pneumoniae was studied in batch cultures under N2 flow and four airflow systems. Different byproducts were formed under different aeration conditions. An anaerobic/aerobic combined fed-batch culture was developed giving 70 g 1,3-propanediol l(-1) and 16 g 2,3-butanediol l(-1) with total diol yield of 0.6 mol(-1) glycerol.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Aerobiosis / physiology
  • Bioreactors / microbiology*
  • Cell Culture Techniques / methods*
  • Cell Proliferation
  • Klebsiella pneumoniae / growth & development*
  • Klebsiella pneumoniae / metabolism*
  • Oxygen / metabolism*
  • Propylene Glycols / metabolism*

Substances

  • Propylene Glycols
  • 1,3-propanediol
  • Oxygen