Abstract
A new homoerythrina alkaloid, C-3-epi-wilsonione (1), a new tetraflavonoid, taiwanhomoflavone C (2), and a new stereoisomer of desmethylcephalotaxinone (3) have been isolated from the leaves and heartwood of Cephalotaxus wilsoniana, respectively. The structures were elucidated by spectroscopic methods. Compound 1 showed cytotoxic activity against a number of human cancer cell lines in vitro.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / chemistry
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Alkaloids / isolation & purification*
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Alkaloids / pharmacology
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Cephalotaxus / chemistry*
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Drug Screening Assays, Antitumor
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Epoxy Compounds / chemistry
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Epoxy Compounds / isolation & purification*
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Epoxy Compounds / pharmacology
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Flavonoids / chemistry
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Flavonoids / isolation & purification*
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Flavonoids / pharmacology
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Humans
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Molecular Structure
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Plant Leaves / chemistry
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Plants, Medicinal / chemistry*
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Taiwan
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Tumor Cells, Cultured
Substances
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Alkaloids
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Antineoplastic Agents, Phytogenic
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C-3-epi-wilsonione
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Epoxy Compounds
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Flavonoids
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taiwanhomoflavone C