Consensus opinion from the antibody working group on the diagnosis, reporting, and risk assessment for antibody-mediated rejection and desensitization protocols

Transplantation. 2004 Jul 27;78(2):181-5. doi: 10.1097/


During the past few decades, much of the experimental and clinical effort in solid-organ transplantation has been directed toward ameliorating or abrogating T-cell-mediated responses. As a result, universally understood and accepted nomenclature and diagnostic criteria have evolved. Humoral immunity in transplantation has yet to undergo a similar renaissance. Readers of transplant journals regularly find it difficult and often impossible to interpret data on the diagnosis and management of antibody-mediated rejection. The Antibody Working Group was assembled in an attempt to provide guidelines for the standardization of nomenclature, diagnostic criteria, reporting, antibody profiling, and risk assessment.

Publication types

  • Consensus Development Conference
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Graft Rejection / immunology*
  • Graft Rejection / prevention & control*
  • Humans
  • Immunosuppression / methods*
  • Isoantibodies / immunology*
  • Models, Immunological
  • T-Lymphocytes / immunology*
  • Transplantation Conditioning / methods


  • Isoantibodies