Development of an expert system knowledge base: a novel approach to promote guideline congruent asthma care

J Asthma. 2004 Jun;41(4):385-402. doi: 10.1081/jas-120026098.


Existing guidelines for the clinical management of asthma provide a good framework for such tasks as diagnosing asthma, determining severity, and prescribing pharmacological treatment. Guidance is less explicit, however, about establishing a patient-provider partnership and overcoming barriers to asthma management by patients in a way that can be easily adopted in clinical practice. We report herein the first developmental phase of the "Stop Asthma" expert system. We describe the establishment of a knowledge base related to both the clinical management of asthma and the enhancement of patient and family self-management (including environmental management). The resultant knowledge base comprises 142 multilayered decision rules that describe clinical and behavioral management in three domains: 1) determination of asthma severity and control; 2) pharmacotherapy, including prescription of medicine for chronic maintenance, acute exacerbation, exercise pretreatment, and rhinitis relief; and 3) patient self-management, including the process of intervening to facilitate the patient's asthma medication management, environmental control, and well-visit scheduling. The knowledge base provides a systematic and accessible approach for intervening with family asthma-related behaviors.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Asthma / diagnosis
  • Asthma / therapy*
  • Child
  • Decision Support Systems, Clinical*
  • Expert Systems*
  • Guideline Adherence
  • Health Behavior
  • Humans
  • Knowledge
  • Practice Guidelines as Topic
  • Self Care
  • Severity of Illness Index