A simple and efficient L-prolinamide-catalyzed alpha-selenenylation reaction of aldehydes

Wei Wang; Jian Wang; Hao Li

doi:10.1021/ol0488946

A simple and efficient L-prolinamide-catalyzed alpha-selenenylation reaction of aldehydes

Org Lett. 2004 Aug 5;6(16):2817-20. doi: 10.1021/ol0488946.

Authors

Wei Wang¹, Jian Wang, Hao Li

Affiliation

¹ Department of Chemistry, University of New Mexico, Albuquerque, NM 87131-0001, USA. wwang@unm.edu

PMID: 15281777
DOI: 10.1021/ol0488946

Abstract

An efficient and simple l-prolinamide-catalyzed alpha-selenenylation reaction of aldehydes with N-(phenylseleno)phthalimide has been developed for the efficient preparation of alpha-phenylselenoaldehydes. Such compounds are versatile building blocks for the synthesis of alpha,beta-unsaturated aldehydes, allylic alcohols, and amines. [reaction: see text]