Fatal, complete splenic infarction and hepatic infection due to disseminated Trichosporon beigelii infection: CT findings

Abdom Imaging. 2004 Mar-Apr;29(2):228-30. doi: 10.1007/s00261-003-0099-6.


We report on a 56-year-old woman with acute lymphocytic leukemia who presented with right upper quadrant pain, fever, nausea, and vomiting. Laboratory studies confirmed fungemia with Trichosporum beigelii, and contrast-enhanced computed tomography of the abdomen demonstrated numerous low-attenuation liver lesions and a hypodense spleen with capsular enhancement suggestive of complete splenic infarction. Subsequent splenectomy confirmed that the spleen was completely infarcted and infiltrated with Trichosporum. The patient had a difficult postoperative course and died despite aggressive antifungal therapy.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Combined Modality Therapy
  • Contrast Media
  • Fatal Outcome
  • Female
  • Humans
  • Middle Aged
  • Mycoses / complications
  • Mycoses / diagnostic imaging*
  • Mycoses / therapy
  • Opportunistic Infections / diagnostic imaging*
  • Opportunistic Infections / therapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
  • Splenectomy
  • Tomography, X-Ray Computed*
  • Trichosporon


  • Antifungal Agents
  • Contrast Media