The role of a lipido-sterolic extract of Serenoa repens in the management of lower urinary tract symptoms associated with benign prostatic hyperplasia

BJU Int. 2004 Aug;94(3):338-44. doi: 10.1111/j.1464-410X.2004.04962.x.

Abstract

OBJECTIVE To examine the clinical profile of medication derived from a lipido-sterolic extract of Serenoa repens (saw palmetto) for managing lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). METHODS We reviewed clinical trials involving extracts of S. repens, focusing on the benefit/risk ratio in patients with BPH. RESULTS S. repens extract significantly reduces the symptoms of BPH, increases urinary flow, improves the quality of life and is well tolerated. CONCLUSION Analysis of the overall clinical database indicates that extract of S. repens may be considered a viable first-line therapy for treating LUTS.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Androgen Antagonists / administration & dosage*
  • Clinical Trials as Topic
  • Drug Administration Schedule
  • Humans
  • Male
  • Meta-Analysis as Topic
  • Patient Compliance
  • Plant Extracts / administration & dosage*
  • Prostatic Hyperplasia / drug therapy*
  • Prostatic Hyperplasia / physiopathology
  • Quality of Life
  • Serenoa
  • Urinary Retention / drug therapy*
  • Urination / physiology

Substances

  • Androgen Antagonists
  • Plant Extracts
  • saw palmetto extract