A deformity consisting of a single orbital fossa with absent globes with proboscis like structure on forehead is described in a 1200 gram female neonate who died immediately after birth. This neonate was born to a 35 years old Para VIII mother at term. Observations from clinical and post mortem examination are presented and literature review made. Because of its rare occurrence and tentative evidence for both genetic and environmental etiologies, reporting of cases of Cyclopia is encouraged.