The Gly1057Asp polymorphism in IRS-2 interacts with obesity to affect beta cell function

Diabetologia. 2004 Apr;47(4):759-61. doi: 10.1007/s00125-003-1302-6.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Body Composition / physiology
  • C-Peptide / metabolism
  • Humans
  • Insulin Receptor Substrate Proteins
  • Intracellular Signaling Peptides and Proteins
  • Islets of Langerhans / physiopathology*
  • Obesity / genetics*
  • Obesity / physiopathology*
  • Phenotype
  • Phosphoproteins / genetics*
  • Polymorphism, Genetic / genetics*

Substances

  • C-Peptide
  • IRS2 protein, human
  • Insulin Receptor Substrate Proteins
  • Intracellular Signaling Peptides and Proteins
  • Phosphoproteins