Three new cytotoxic cyclic acylpeptides from marine Bacillus sp

Chem Pharm Bull (Tokyo). 2004 Aug;52(8):1029-30. doi: 10.1248/cpb.52.1029.

Abstract

Three new cytotoxic cyclopeptides belonging to iturin class have been isolated from marine bacterium Bacillus sp. These three compounds have the cytotoxic activities. Their structures were determined based on chemical analysis and all kinds of spectroscopic techniques.

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / isolation & purification*
  • Antineoplastic Agents / pharmacology
  • Bacillus / chemistry*
  • HCT116 Cells
  • Humans
  • Inhibitory Concentration 50
  • Marine Biology
  • Molecular Structure
  • Peptides, Cyclic / chemistry
  • Peptides, Cyclic / isolation & purification*
  • Peptides, Cyclic / pharmacology

Substances

  • Antineoplastic Agents
  • Peptides, Cyclic