Prenatal origin of GATA1 mutations may be an initiating step in the development of megakaryocytic leukemia in Down syndrome

Blood. 2004 Sep 1;104(5):1588-9. doi: 10.1182/blood-2004-04-1563.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • DNA-Binding Proteins / genetics*
  • Down Syndrome / complications*
  • Down Syndrome / genetics*
  • Erythroid-Specific DNA-Binding Factors
  • GATA1 Transcription Factor
  • Humans
  • Leukemia, Megakaryoblastic, Acute / complications*
  • Leukemia, Megakaryoblastic, Acute / genetics*
  • Mutation
  • Transcription Factors / genetics*

Substances

  • DNA-Binding Proteins
  • Erythroid-Specific DNA-Binding Factors
  • GATA1 Transcription Factor
  • GATA1 protein, human
  • Transcription Factors