The sweet and the bitter of mammalian taste

Curr Opin Neurobiol. 2004 Aug;14(4):423-7. doi: 10.1016/j.conb.2004.06.003.

Abstract

The discovery of two families of mammalian taste receptors has provided important insights into taste recognition and taste perception. Recent studies have examined the receptors and signaling pathways that mediate sweet, bitter, and amino acid taste detection in mammals. These studies demonstrate that taste cells are selectively tuned to different taste modalities and clarify the logic of taste coding in the periphery.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Isoenzymes / physiology
  • Membrane Proteins / physiology
  • Neurons, Afferent / cytology
  • Neurons, Afferent / physiology*
  • Phospholipase C beta
  • Receptors, G-Protein-Coupled / genetics
  • Signal Transduction / genetics
  • TRPM Cation Channels
  • Taste / physiology*
  • Taste Buds / cytology
  • Taste Buds / physiology*
  • Type C Phospholipases / physiology

Substances

  • Isoenzymes
  • Membrane Proteins
  • Receptors, G-Protein-Coupled
  • TRPM Cation Channels
  • TRPM5 protein, human
  • taste receptors, type 1
  • taste receptors, type 2
  • Type C Phospholipases
  • Phospholipase C beta