Association between exercise and quality of life in multiple myeloma cancer survivors

Support Care Cancer. 2004 Nov;12(11):780-8. doi: 10.1007/s00520-004-0668-4.


Goals of the work: The goal of this study was to examine the association between exercise and quality of life (QOL) in multiple myeloma cancer survivors.

Patients and methods: Using a retrospective design, 156 multiple myeloma cancer survivors were mailed a questionnaire that assessed self-reported exercise behavior over three periods (prediagnosis, active treatment, and off-treatment) and QOL.

Main results: The response rate was 56% (88/ 156). Descriptive analyses indicated that 6.8% and 20.4% of survivors met national exercise guidelines during active and off-treatment periods, respectively. Exercise during active treatment and off-treatment were positively associated with overall QOL and all subdomains of QOL (all P<0.05) except physical wellbeing.

Conclusions: A low percentage of multiple myeloma cancer survivors are exercising regularly either during active or off-treatment periods. Survivors who report more exercise during these periods also report higher QOL. These findings suggest that a randomized controlled trial is warranted.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Combined Modality Therapy
  • Exercise / physiology*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Multiple Myeloma / diagnosis
  • Multiple Myeloma / mortality
  • Multiple Myeloma / rehabilitation*
  • Multivariate Analysis
  • Patient Satisfaction
  • Probability
  • Quality of Life*
  • Radiotherapy / methods
  • Retrospective Studies
  • Risk Assessment
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Sex Factors
  • Sickness Impact Profile
  • Surveys and Questionnaires
  • Survivors / psychology*