Carotenoids are isoprenoid pigmented compounds that are present in representatives from practically all eukaryotic and prokaryotic taxa. In plants, carotenoids are synthesized and normally sequestered in plastids as lipophilic C40 constituents. However, they are also subjected to oxidative remodeling initiated by specific carotenoid cleavage dioxygenases. Primary products resulting from these reactions undergo modifications involving oxido-reduction, dehydratation rearrangement, and glycosylation. This review focuses on only a few of these derivatives for which the enzymes and genes involved have been characterized. The compartmentation of this metabolism and its significance have also been considered.