Colonization with extraintestinal pathogenic Escherichia coli among nursing home residents and its relationship to fluoroquinolone resistance

Antimicrob Agents Chemother. 2004 Sep;48(9):3618-20. doi: 10.1128/AAC.48.9.3618-3620.2004.

Abstract

In a cross-sectional fecal prevalence survey involving 49 residents of a Veterans Affairs nursing home, 59% of subjects were colonized with extraintestinal pathogenic Escherichia coli (ExPEC), 22% were colonized with adhesin-positive E. coli, and 51% were colonized with fluoroquinolone-resistant E. coli. Among 80 unique isolates, adhesins correlated negatively and aerobactin correlated positively with fluoroquinolone resistance.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adhesins, Bacterial / metabolism
  • Anti-Bacterial Agents / pharmacology
  • Drug Resistance, Bacterial
  • Escherichia coli / genetics
  • Escherichia coli / growth & development*
  • Escherichia coli / metabolism
  • Escherichia coli Infections / microbiology*
  • Feces / microbiology
  • Fluoroquinolones / pharmacology
  • Humans
  • Hydroxamic Acids / metabolism
  • Nursing Homes
  • Reverse Transcriptase Polymerase Chain Reaction
  • United States
  • United States Department of Veterans Affairs
  • Virulence Factors

Substances

  • Adhesins, Bacterial
  • Anti-Bacterial Agents
  • Fluoroquinolones
  • Hydroxamic Acids
  • Virulence Factors
  • aerobactin