Stenosis of pulmonary veins in Down syndrome

J Paediatr Child Health. 1992 Apr;28(2):192-5. doi: 10.1111/j.1440-1754.1992.tb02641.x.


Two patients with Down syndrome, intracardiac communications and elevated pulmonary arteriolar resistance presented early in life. Both patients had significant stenosis of pulmonary veins. The progressive nature of the stenosis is illustrated in one patient. Pulmonary venous stenosis in Down syndrome has been recorded only twice before in the literature, and may play a part in the early onset of pulmonary vascular occlusive disease in some patients.

Publication types

  • Case Reports

MeSH terms

  • Cardiac Catheterization
  • Cineangiography
  • Down Syndrome / complications*
  • Echocardiography
  • Electrocardiography
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Pulmonary Valve Stenosis / complications*
  • Pulmonary Valve Stenosis / diagnosis
  • Pulmonary Valve Stenosis / pathology
  • Pulmonary Veins / pathology