Nicorandil: a review of its use in the management of stable angina pectoris, including high-risk patients

Drugs. 2004;64(17):1941-55. doi: 10.2165/00003495-200464170-00012.

Abstract

Nicorandil (Adancor, Angicor, Dancor, Nikoril [Europe], Ikorel [Europe and Oceania], Sigmart [Japan, Korea and Taiwan]) is an adenosine triphosphate (ATP)-sensitive potassium (KATP) channel agonist with nitrate-like properties used in the management of stable angina pectoris. With well established monotherapeutic antianginal activity and a beneficial effect (when added to optimal antianginal therapy) on clinical outcomes in high-risk patients with stable angina, twice-daily oral nicorandil is a useful alternative or addition to other antianginal therapy.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Angina Pectoris / drug therapy*
  • Animals
  • Area Under Curve
  • Clinical Trials as Topic
  • Humans
  • Middle Aged
  • Nicorandil / pharmacology*
  • Nicorandil / therapeutic use*
  • Vasodilator Agents / pharmacology*
  • Vasodilator Agents / therapeutic use*

Substances

  • Vasodilator Agents
  • Nicorandil