Prevalence of hepatitis C virus among patients with liver disease in the Republic of Yemen

East Mediterr Health J. 2001 Jul-Sep;7(4-5):771-8.

Abstract

We investigated 143 patients with various classes of liver disease and 120 healthy subjects for serological markers of hepatitis C and B viruses. We found a prevalence rate of 37.1% of anti-HCV markers in patients with liver disease (cases), and 4.2% and in the control group. HBsAg was detected in 33.6% of cases and 13.3% of the controls. Anti-HCV and HBsAg were detected in 7.7% of cases but were not detected in the controls. Anti-HCV, HBsAg, anti-HBe and anti-HDV were detected in three patients. Serum protein electrophoresis results showed elevated gammaglobulin and low albumin in patients positive for anti-HCV who had liver disease.

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Age Distribution
  • Biomarkers / blood
  • Blood Protein Electrophoresis
  • Case-Control Studies
  • Child
  • Chronic Disease
  • Female
  • Hepatitis B / blood
  • Hepatitis B / complications*
  • Hepatitis B / epidemiology
  • Hepatitis B / immunology
  • Hepatitis B Surface Antigens / blood
  • Hepatitis B e Antigens / blood
  • Hepatitis C / blood
  • Hepatitis C / complications*
  • Hepatitis C / epidemiology
  • Hepatitis C / immunology
  • Hepatitis C Antibodies / blood
  • Hepatitis D / blood
  • Hepatitis D / complications
  • Hepatitis D / epidemiology
  • Hepatitis D / immunology
  • Hospitals, University
  • Humans
  • Liver Diseases / epidemiology
  • Liver Diseases / virology*
  • Male
  • Middle Aged
  • Population Surveillance
  • Seroepidemiologic Studies
  • Sex Distribution
  • Yemen / epidemiology

Substances

  • Biomarkers
  • Hepatitis B Surface Antigens
  • Hepatitis B e Antigens
  • Hepatitis C Antibodies