Wireless capsule video endoscopy compared to barium follow-through and computerised tomography in patients with suspected Crohn's disease--final report

Dig Liver Dis. 2004 Aug;36(8):519-22. doi: 10.1016/j.dld.2004.03.011.

Abstract

Background: Wireless capsule endoscopy is a superior diagnostic tool to barium small bowel follow-through and enteroscopy in diagnosing patients with occult blood loss.

Aim: To compare capsule endoscopy with barium follow-through and entero-computerised tomography in patients with suspected Crohn's disease.

Subjects and methods: Thirty-five patients with suspected Crohn's disease underwent the three examinations. The radiologist and gastroenterologist were blinded to each other's results. In cases of discrepancy, colonoscopy and ileoscopy were performed.

Results: Thirty-five patients (22 males), mean age 28.4 years, were included. Eighty-eight percent had abdominal pain, 83% had diarrhoea and 69% had weight loss. The diagnostic yield of capsule endoscopy was 77% versus 23% and 20% of barium and computerised tomography examinations, respectively (P < 0.05). The capsule detected all of the lesions diagnosed by barium follow-through and entero-computerised tomography.

Conclusions: Capsule endoscopy is a superior and more sensitive diagnostic tool than barium follow-through and entero-computerised tomography in patients with suspected Crohn's disease.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Barium Sulfate
  • Capsules
  • Crohn Disease / diagnosis*
  • Endoscopy, Gastrointestinal / methods*
  • Humans
  • Male
  • Occult Blood
  • Tomography, X-Ray Computed
  • Video Recording / methods*

Substances

  • Capsules
  • Barium Sulfate