A case of cellulitis complicating Campylobacter jejuni subspecies jejuni bacteremia and review of the literature

Eur J Clin Microbiol Infect Dis. 2004 Sep;23(9):718-21. doi: 10.1007/s10096-004-1201-x. Epub 2004 Aug 24.

Abstract

Infection with Campylobacter species is a predominant cause of food-borne gastroenteritis in the industrialized world. Bacteremia is detected in <1% of patients with diarrhea, mainly in immunocompromised hosts or those in the extremes of age. Reported here is the case of a 78-year-old, immunocompromised male patient with Campylobacter jejuni subsp. jejuni bacteremia complicated by cellulitis. The infection was characterized by a protracted course with several recurrences and refractoriness to multiple antibiotic regimens, responding only to a prolonged course of meropenem treatment. The frequency of cellulitis as reflected in previously reported series of Campylobacter bacteremia and the clinical characteristics of this difficult-to-treat infection are reviewed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Bacteremia / complications
  • Bacteremia / diagnosis*
  • Bacteremia / drug therapy
  • Campylobacter Infections / complications
  • Campylobacter Infections / diagnosis*
  • Campylobacter Infections / drug therapy
  • Campylobacter jejuni / isolation & purification*
  • Cellulitis / drug therapy*
  • Cellulitis / microbiology*
  • Drug Therapy, Combination / therapeutic use
  • Follow-Up Studies
  • Humans
  • Immunocompromised Host
  • Male
  • Meropenem
  • Myelodysplastic Syndromes / immunology
  • Myelodysplastic Syndromes / therapy
  • Recurrence
  • Risk Assessment
  • Roxithromycin / administration & dosage
  • Severity of Illness Index
  • Thienamycins / administration & dosage
  • Treatment Outcome

Substances

  • Thienamycins
  • Roxithromycin
  • Meropenem