[Clinical evaluation of integration of transcatheter arterial chemoembolization and traditional Chinese medicine in treating metastatic liver cancer]

Zhong Xi Yi Jie He Xue Bao. 2003 Sep;1(3):187-8, 233. doi: 10.3736/jcim20030312.
[Article in Chinese]

Abstract

Objective: To evaluate the treatment effect, quality of life and side-effect of transcatheter arterial chemoembolization (TACE) and traditional Chinese medicine (TCM) in treating metastatic liver cancer.

Methods: Thirty-nine cases of colon metastatic liver cancer were randomly divided into two groups. Both TACE and TCM were used in the treatment group, while only TACE was used in the control group. The drug used in TACE included floxuridine, pirarubicin, cisplatin, and the herbs for strengthening the spleen and regulating Qi were used in TCM.

Results: The response rate in the treatment group was 30% (45% including minor remission patients), and the median survival time was 18.6 months. While in the control group the response rate was 15.8% (36.8% including minor remission patients), and the median survival time was 14.3 months. The 1-, 2-, 3- year survival rates of treatment group and the control group were 70.2%, 40.3%, 13.0% and 68.7%, 29.5%, 10.3% respectively. There were fewer other organ metastases in the treatment group. The score from the EORTC quality of life questionnaire QLQ-C30 in treatment group was higher than that in the control group.

Conclusion: Integration of TACE and TCM in treating colon metastatic liver cancer has better results.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Catheterization / methods
  • Chemoembolization, Therapeutic / methods*
  • Colonic Neoplasms / pathology
  • Drugs, Chinese Herbal / administration & dosage*
  • Drugs, Chinese Herbal / therapeutic use
  • Female
  • Humans
  • Liver Neoplasms / drug therapy*
  • Liver Neoplasms / mortality
  • Liver Neoplasms / secondary
  • Male
  • Middle Aged
  • Quality of Life
  • Survival Rate
  • Treatment Outcome

Substances

  • Drugs, Chinese Herbal