Abstract
Radial glial proliferation is a critical step in the construction of cerebral cortex. In this issue of Neuron, Weissman and colleagues use time-lapse calcium imaging techniques to demonstrate that spontaneous calcium waves sweeping through cohorts of radial glia in the ventricular zone can modulate their proliferation during cerebral cortical development.
MeSH terms
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Adenosine Triphosphate / metabolism
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Animals
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Calcium Signaling / physiology*
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Cell Communication / physiology
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Cell Differentiation / physiology
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Cell Division / physiology
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Cell Movement / physiology
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Cerebral Cortex / cytology
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Cerebral Cortex / embryology*
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Cerebral Cortex / metabolism
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Humans
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Neuroglia / cytology
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Neuroglia / metabolism*
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Neurons / cytology
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Neurons / metabolism*