Calcium waves rule and divide radial glia

Neuron. 2004 Sep 2;43(5):599-601. doi: 10.1016/j.neuron.2004.08.030.

Abstract

Radial glial proliferation is a critical step in the construction of cerebral cortex. In this issue of Neuron, Weissman and colleagues use time-lapse calcium imaging techniques to demonstrate that spontaneous calcium waves sweeping through cohorts of radial glia in the ventricular zone can modulate their proliferation during cerebral cortical development.

Publication types

  • Comment
  • Review

MeSH terms

  • Adenosine Triphosphate / metabolism
  • Animals
  • Calcium Signaling / physiology*
  • Cell Communication / physiology
  • Cell Differentiation / physiology
  • Cell Division / physiology
  • Cell Movement / physiology
  • Cerebral Cortex / cytology
  • Cerebral Cortex / embryology*
  • Cerebral Cortex / metabolism
  • Humans
  • Neuroglia / cytology
  • Neuroglia / metabolism*
  • Neurons / cytology
  • Neurons / metabolism*

Substances

  • Adenosine Triphosphate