Plasmodesmata as a supracellular control network in plants

Nat Rev Mol Cell Biol. 2004 Sep;5(9):712-26. doi: 10.1038/nrm1470.


The evolution of intercellular communication had an important role in the increasing complexity of both multicellular and supracellular organisms. Plasmodesmata, the intercellular organelles of the plant kingdom, establish an effective pathway for local and long-distance signalling. In higher plants, this pathway involves the trafficking of proteins and various forms of RNA that function non-cell-autonomously to affect developmental programmes.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Cell Communication / physiology*
  • Green Fluorescent Proteins
  • Luminescent Proteins / metabolism
  • Models, Biological
  • Plant Development
  • Plant Diseases
  • Plant Physiological Phenomena*
  • Plant Proteins / metabolism*
  • Plants / anatomy & histology
  • Plasmodesmata / metabolism*
  • Protein Transport
  • RNA, Plant / metabolism


  • Luminescent Proteins
  • Plant Proteins
  • RNA, Plant
  • Green Fluorescent Proteins