[The effect of bromantan on the sexual behavior and conception in rats]

Eksp Klin Farmakol. 2004 May-Jun;67(3):34-7.
[Article in Russian]


The results of experiments on rats showed that the psychotropic drug bromantan affects the sexual behavior and pairing activity. A three-day treatment with bromantan (30 and 300 mg/kg, p.o.) predominantly increased the sexual proceptivity, whereas a chronic administration (for 2 months in males and 2 weeks in females) produced a dose-dependent increase in both proceptivity and receptivity. The observed effects are probably related to the dopamine-positive action of bromantan.

MeSH terms

  • Amantadine / analogs & derivatives*
  • Amantadine / pharmacology*
  • Animals
  • Female
  • Male
  • Pregnancy
  • Pregnancy, Animal / drug effects*
  • Psychotropic Drugs / pharmacology*
  • Rats
  • Sexual Behavior, Animal / drug effects*


  • Psychotropic Drugs
  • Amantadine
  • bromantane