Chemical genomics in yeast

Genome Biol. 2004;5(9):240. doi: 10.1186/gb-2004-5-9-240. Epub 2004 Aug 27.


Many drugs have unknown, controversial or multiple mechanisms of action. Four recent 'chemical genomic' studies, using genome-scale collections of yeast gene deletions that were either arrayed or barcoded, have presented complementary approaches to identifying gene-drug and pathway-drug interactions.

Publication types

  • Review

MeSH terms

  • Genomics / methods*
  • Proteome / drug effects*
  • Proteome / genetics*
  • Saccharomyces cerevisiae / genetics*


  • Proteome