Multiple congenital melanocytic naevi presenting with neurofibroma-like lesions complicated by malignant melanoma

Clin Exp Dermatol. 2004 Sep;29(5):473-6. doi: 10.1111/j.1365-2230.2004.01562.x.

Abstract

Giant congenital pigmented naevi and neurofibromatosis (NF-1) may rarely occur together. We report an unusual case where extensive congenital melanocytic naevi were associated with neurofibroma-like lesions that were clinically and histologically confused with neurofibromatosis. The development of malignant melanomas within the pigmented and pendulous lesions representing multiple congenital melanocytic naevi highlights the importance of an accurate diagnosis and a close follow-up of such patients.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Female
  • Humans
  • Melanoma / pathology*
  • Middle Aged
  • Neoplasms, Multiple Primary / congenital*
  • Neoplasms, Multiple Primary / pathology*
  • Neurofibroma / pathology*
  • Nevus, Pigmented / congenital*
  • Nevus, Pigmented / pathology
  • Skin Neoplasms / congenital*
  • Skin Neoplasms / pathology