Breast fibroadenomas in renal transplant recipients

Transplant Proc. Jul-Aug 2004;36(6):1839-40. doi: 10.1016/j.transproceed.2004.07.013.

Abstract

Breast fibroadenomas are the most common solid lesions found in young women. We report on four patients who underwent renal transplantation and developed bilateral fibroadenomas while on cyclosporine (CsA). One patient developed symptomatic giant fibroadenomas and underwent bilateral mammoplasty. A significant decrease in the size of the breasts was noticed after switching to tacrolimus in three patients. Awareness of the association between CsA and fibroadenomas should help to achieve the correct diagnosis in transplant patients without subjecting them to unnecessary procedures.

MeSH terms

  • Breast Neoplasms / chemically induced*
  • Cyclosporine / adverse effects*
  • Female
  • Fibroadenoma / chemically induced*
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Immunosuppressive Agents / therapeutic use
  • Kidney Transplantation / immunology*
  • Tacrolimus / therapeutic use

Substances

  • Immunosuppressive Agents
  • Cyclosporine
  • Tacrolimus