Use of tetracycline and niacinamide for treatment of autoimmune skin disease in 31 dogs

J Am Vet Med Assoc. 1992 May 15;200(10):1497-500.

Abstract

A combination of niacinamide and tetracycline was used to treat 31 dogs with various autoimmune skin diseases (discoid lupus erythematosus, pemphigus foliaceus, pemphigus erythematosus, and bullous pemphigoid). Of the 20 dogs with discoid lupus erythematosus, 70% had excellent or good response to treatment. Serious side effects were not noticed in any dog.

MeSH terms

  • Animals
  • Autoimmune Diseases / drug therapy
  • Autoimmune Diseases / veterinary*
  • Dog Diseases / drug therapy*
  • Dogs
  • Drug Combinations
  • Female
  • Lupus Erythematosus, Discoid / drug therapy
  • Lupus Erythematosus, Discoid / veterinary
  • Niacinamide / therapeutic use*
  • Pemphigoid, Bullous / drug therapy
  • Pemphigoid, Bullous / veterinary
  • Pemphigus / drug therapy
  • Pemphigus / veterinary*
  • Skin Diseases / drug therapy
  • Skin Diseases / veterinary*
  • Tetracycline / therapeutic use*

Substances

  • Drug Combinations
  • Niacinamide
  • Tetracycline