Typical and subtle atypical presentations of endometriosis

Curr Opin Obstet Gynecol. 2004 Oct;16(5):431-7. doi: 10.1097/00001703-200410000-00013.


Purpose of review: To review the concept of typical, subtle and invisible endometriosis and analyze the evolution and progression of the disease, as well as some factors possibly involved in the pathogenesis.

Recent findings: Although rejected by Redwine, the concept of non-visible endometriosis has been proven to exist. Some new ideas on the implication of reactive oxygen species in the development of endometriosis and its early stages are described here.

Summary: The increased diagnosis of endometriosis can be explained not only by the increased experience and ability of the surgeon to detect typical and non-typical endometriotic lesions, but also by a better understanding of the pathogenesis.

Publication types

  • Review

MeSH terms

  • Endometriosis / pathology*
  • Endometriosis / physiopathology
  • Erythrocytes / pathology
  • Female
  • Humans
  • Iron / analysis
  • Iron Overload / pathology
  • Menstruation / physiology
  • Peritoneal Diseases / pathology*
  • Peritoneal Diseases / physiopathology
  • Peritoneum / chemistry


  • Iron